Delay Spray May Enable Men
To Treat Premature Ejaculation Themselves!
Anesthetic Spray On The Penis
Although premature ejaculation is certainly one of the most common sexual dysfunctions in men, there is a definite lack of pharmacological treatments for it.
Indeed Dapoxetine is one of the few licensed pharmaceuticals available for PE, although its license has only been granted in certain parts of Europe.
But if both biological and psychological factors are responsible for causing PE, then it's perhaps surprising that there are not more pharmaceuticals which have been developed to treat the biological aspects of the condition.
However, anesthetic sprays - also called topical desensitizing agents - have been around for a long time.
Indeed they are probably the longest established method of treating PE. The application of topical anesthetic, or desensitizing agent, to the glans of the penis to improve latency time is not a new idea, because back in the 1930s benzocaine or lignocaine were being prescribed for this very purpose.
In Korea, a compound known as SS cream containing natural ingredients has been used for many years to desensitize the penile glans and achieve longer lovemaking.
Recently there been several new compounds developed for topical desensitization including the TEMPE spray (see below), and a mixture of local anesthetic dylonine and alprostadil.
All of these trials demonstrate a significant increase in latency time, although there are some minor side-effects like penile numbness and in some cases a burning sensation.
One problem has been the lack of uniformity in the delivery system of such anesthetics, a problem which is potentially overcome by the TEMPE spray.
This has made a large leap forward in terms of controlled delivery and is easy to use and well tolerated.
Condom And Anesthetic Use To Reduce Penile Sensitivity
Some men have tried using two ordinary condoms to reduce sensitivity - but this is a dangerous strategy since "double-bagging" can lead to condom tear and breakage. Not recommended.
If you are going to try this approach to overcoming rapid ejaculation, I recommend you use a delay condom which may enable you to last longer.
They reduce the sensitivity of the penis with a predetermined amount of anesthetic in the teat of the penis, which spreads across the gland and reduces sensitivity to sexual stimulation. This had the added advantage that the cream does not spread to the partner's vagina.
Application of local anesthetic to the inside of a condom, where the cream is limited to contact with the man's penis, is a definite improvement over strategies where the cream is simply smeared onto the glans and no condom is used.
This is because even when the cream is washed off before penetration, the possibility remains of reducing the sensations for the woman in her vagina.
But despite all the claims, what's interesting is that these systems haven't achieved particularly widespread acceptance or popularity, which suggests that they are either uncomfortable or impractical to use.
As one female user wrote: "Did things go completely numb as the male tester feared? Apparently things felt slightly odd - more a diminished sensation but not totally numb as he'd feared! Things did last longer, but he summed up the whole thing like someone kept moving the goal posts: just as he got near ejaculating, they were moved again. It made for an interesting night, is all I'm saying...... "
But another user observed: "Using a free sample of one of these condoms (a Durex Performa), I discovered sensation was normal until several minutes after donning the condom, at which point the sensation slowly diminished until my glans had hardly any sensation at all. Still, my erection remained and so, remarkably, did the pleasure. Durex claims that Performa delays a man's orgasm by minutes, but in my case the effect was so strong that I couldn't ejaculate at all."
A few men have treated premature ejaculation with anesthetic cream successfully. The anesthetic cream with lignocaine can be rubbed into the glans and frenulum up to half an hour before intercourse.
If the penis is washed well before sex play begins, it is even possible for the woman to offer fellatio without any unpleasant taste. However, a lot of men have reported that these creams are useless: they may find that if they can experiment, this problem can be resolved.
For example, try using the cream an hour before sex, or use twice the suggested application of cream; with such experiments, you may discover your exact personal requirements.
The TEMPE Spray
Researchers from both the Netherlands and the UK carried out an assessment of this new treatment in 54 men with premature ejaculation, using a control group of men and a treatment group.
All the men in both groups reported a tendency to ejaculate after about one minute of sexual intercourse prior to treatment.
This treatment is a spray which men apply to the glans of their penis before intercourse. Of course we have seen anesthetic as a treatment before, not least in condoms coated internally with an anesthetic lotion.
But these do not seem to have been particularly successful. The new medication developed and tested by the researchers is called the TEMPE spray (which stands for Topical Eutectic Mixture for Premature Ejaculation); it offers a combination of lidocaine and prilocaine which can be applied by spray to the glans of the penis.
According to initial reports from men who came quickly during sex, the average increase in the duration of intercourse in men using the product is just over four minutes.
In the same study, the placebo or control group, who were given a spray which contained no active chemicals, managed to extend intercourse by just over forty five seconds.
The study was conducted on heterosexual couples who had been in a stable one to one relationship for at least three months and who were prepared to try having sexual intercourse seven or more times during the ten-week period over which the study was conducted.
This research on the new treatment for premature ejaculation was carried out in seven medical centers in Sheffield, Manchester, Durham, Plymouth, Belfast, London and The Hague on men with an age range of 18 to 75, and an average age of 39.
These men had been having ejaculatory problems (that is, they came too quickly) for a period of between seven months and over thirty years; the average length of time was nine and a half years.
The men in the TEMPE group were instructed to apply three measured amounts of the medication by spray about a quarter of an hour before intercourse, a delivery which administered a total of 22.5mg of lidocaine and 7.5mg of prilocaine to the glans of their penis.
The placebo group had a spray which contained no active ingredients. Both sets of men were told not to administer more than one application in any twenty four hour period.
This was an attempt to stop the men affecting their own latency time by having more than one ejaculation in any twenty four hour period.
(Though it may have been simpler and possibly more accurate to simply tell the men not to have more than one ejaculation in a day: this would have ruled out the possibility that they would masturbate to orgasm. The instruction not to use the spray seems to imply the researchers equated ejaculations with intercourse.)
Another product which works in the same way - PSD 502.
To get some sense of the increase in time between penetration and ejaculation, the men were given a stopwatch so that they could measure the duration of intercourse. (Alternatively their partners could record the time lapse.)
Initial results were promising and encouraging for men who tended to come too quickly. Twenty TEMPE users and roughly the same number of control group men completed the study; about four fifths of all the men said that the premature ejaculation spray was easy to use.
Since one of the complaints about anesthetic creams or lotions designed to treat premature ejaculation when applied to the penis has always been that they can numb the man's partner's vagina, it seems a little surprising that most of the men in the study - and apparently their partners - seemed to have no problems using the spray.
And of course delay condoms are the oldest form of delay treatment for PE.
Nonetheless, the vast majority of the TEMPE users and their partners said that they tolerated the spray well.
The only adverse effects reported were numbness in the penis (three men), the inability to get an erection (one man) and a report form one man's partner of a mild burning sensation each time the couple used the spray.
This latter couple continued with the treatment. A series of medical checks were conducted on the men and these found no adverse medical effects in the areas of vital signs, urine analysis, electrocardiograms, hematology and biochemistry.
Dr Michael Wyllie from Plethora Solutions has observed that only a small number of men with ejaculatory difficulties seek help.
One of the reasons for this may be the lack of a simple drug treatment - therapy and counseling is not with the financial reach of all men - so the application of a topical spray which is well-tolerated, effective, and lacks side-effects is a promising step forward.
He goes on to say that since all the above criteria are fulfilled, TEMPE may offer a convenient, new treatment; it may even be an effective first-line treatment for the condition.
For more information, see: Topical eutectic mixture: an aerosol-delivery form of prilocaine-lidocaine for use in treating premature ejaculation. Dinsmore et al. BJU International. Volume 99, pages 369-375. (February 2007).